Lidocaine Euphoria

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Lidocaine euphoria is a rather unusual side-effect to the administration of Lidocaine as either a Local anesthetic, a Nerve block or more rarely, Intravenous. Pharmaceutically speaking, this is considered to be a potential side-effect of the usage of Lidocaine; however, prior (or current) users of Cocaine appear to be more susceptible to this potential side-effect.

Though chemically relatively dissimilar (Lidocaine (C17H21N04) / Cocaine (C14H22N2O)), it is hypothesized that the mechanism of CNS activity may be the cause for the similar euphoric-producing side-effects of each Drug.

This is entirely different than lidocaine induced anxiety, a side effect of Epinephrine in products containing both Lidocaine and Epinephrine.