Lemierre's syndrome and Lidocaine Euphoria: Difference between pages

From BME Encyclopedia
(Difference between pages)
Jump to navigation Jump to search
(Page conversion via llm-mediawiki-rev -jwm)
 
(Page conversion via llm-mediawiki-rev -jwm)
 
Line 1: Line 1:
'''Lemierre's syndrome''' (also known as '''Lemierre's disease''', '''necrobacillosis''' or post-anginal [[Sepsis|sepsis]]) is an extremely rare disease which has tentatively been linked as a having tongue piercing as a potential trigger. As of mid-2002, there has been a single case, which was that of a 15-year-old boy in San Diego. That said, it is important to note that a single small infection in a piercing can travel inward and become much more serious. (Of course, the same thing can and does happen from paper cuts and even biting your lip).
'''Lidocaine euphoria''' is a rather unusual side-effect to the administration of [[Lidocaine]] as either a [[Local anesthetic]], a [[Nerve block]] or more rarely, [[Intravenous]]. Pharmaceutically speaking, this is considered to be a potential side-effect of the usage of [[Lidocaine]]; however, prior (or current) users of [[Cocaine]] appear to be more susceptible to this potential side-effect.


Lemierre's consists of an oropharyngeal infection (an infection between the soft palate and the epiglottis, the part of your mouth that closes off your throat during swallowing) with anaerobic septicemia (essentially blood poisoning), followed by suppurative thrombophlebitis (when a vein, generally the internal jugular, becomes inflamed from blood clotting) and septic metastases (basically rotting cells spreading more sepsis throughout the body).
Though chemically relatively dissimilar ([[Lidocaine]] (C17H21N04) / [[Cocaine]] (C14H22N2O)), it is hypothesized that the mechanism of CNS activity may be the cause for the similar euphoric-producing side-effects of each [[Drug]].


From the patient's point of view, Lemierre's generally starts with a sore throat, fever, and chills, perhaps with a mild headache. Then nausea, vomiting, and difficulty swallowing set in. After that, the patient suffers a cough, pleuritic chest pain, and dehydration (along with brighter urine). There may be some elevated heart rate and minute hemorrhaging. Blood cultures can confirm the presence of Lemierre's syndrome.
This is entirely different than [[Lidocaine Anxiety (page does not exist)|'''lidocaine induced anxiety''']], a side effect of [[Epinephrine]] in products containing both [[Lidocaine]] and [[Epinephrine]].
 
Recovery from Lemierre's, assuming it's not fatal (the microorganism which causes it is named ''Fusobacterium necrophorum'', literally "spindle shaped rod which brings death"), takes about six to seven months of hospitalization.
 
Apologize for how confusing this entry is — this disease is rather complex and difficult to explain clearly.
 
The important point to realize is: '''A small infection can travel inward and become very serious very quickly.'''

Latest revision as of 07:11, 17 September 2023

Lidocaine euphoria is a rather unusual side-effect to the administration of Lidocaine as either a Local anesthetic, a Nerve block or more rarely, Intravenous. Pharmaceutically speaking, this is considered to be a potential side-effect of the usage of Lidocaine; however, prior (or current) users of Cocaine appear to be more susceptible to this potential side-effect.

Though chemically relatively dissimilar (Lidocaine (C17H21N04) / Cocaine (C14H22N2O)), it is hypothesized that the mechanism of CNS activity may be the cause for the similar euphoric-producing side-effects of each Drug.

This is entirely different than lidocaine induced anxiety, a side effect of Epinephrine in products containing both Lidocaine and Epinephrine.

Retrieved from "https://wiki.bme.com/index.php?title=Lemierre%27s_syndrome&oldid=6126"